Failed to map the path '/YourApplication/App_GlobalResources'

Problem Description:
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Failed to map the path '/YourApplication/App_GlobalResources'.

Troubleshooting Steps:
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Step 1:
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In the folder --> C:\Documents and Settings\All Users\Application Data\Microsoft\Crypto\RSA\MachineKeys
... checked for the key that was 0 KBytes, but none was there if any 0 kb keys we need to delete it

Step 2:
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Run the aspnet_regiis utility in the framework folder:

c:\WINNT\Microsoft.NET\framework\v2.0.50727\aspnet_regiis -i

This will re-register ASP.NET with IIS and re-create the ASPNET account.

Next you need to give permissions to the (nicely refreshed) ASPNET user account to access this folder with Modify permissions:

C:\Documents and Settings\All Users\WINNT\Application Data\Microsoft\Crypto\RSA\MachineKeys

Restart of IIS

Step 3:
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Click the Security Tab under the Properties of the C:\Documents and Settings\All Users\Application Data\Microsoft\Crypto\RSA and add the ASP.NET account with full control

Now it was throwing reportserver.config denied

Gave aspnet permissions on that file that resolved the access denied error

Now it was throwing reportserver not found error

Checked rswebapplication.config and changed the URL
Added reporserver element between reportservervirtualdirectory
Now reset the IIS. Restarted the reporting services

Now browsed the reports and reportserver from IIS as well as URL
It was working fine.